Germ Theory

Lessons on the Historical Context

These lessons and activities will familiarize students with the life, times, and cultural contexts of the 19th and 20th centuries out of which emerged the germ theory of disease. By participating in some or all of these, students will obtain and likely retain conceptual understanding of not only the germ theory of disease but also the nature of science.


Teacher's Toolkit: Reforming Cookbook Labs
http://learningcenter.nsta.org/product_detail.aspx?id=10.2505/4/ss05_029_03_16
  National Science Teachers Association

This article presents 11 different ways of altering cookbook labs so that students understand the intention of the procedure, a step toward allowing more open-ended discovery. For example, given the procedure, students design a data table. Or, the steps in the procedure are mixed up and students have to put them in correct order. The suggested strategies can be applied to historic experiments, such as Redi's experiment to disprove spontaneous generation or Pasteur's swan-necked flask experiments. This approach contrasts with the normal presentation of these famous experiments where students are told what was done, how, why, and the results. Very often students do not understand why the methods were chosen or how the results are logical outcomes. Moreover, students rarely retain any significant conceptual understanding even though they were told the important points. (This online article is free to NSTA members; nonmembers must pay $4.99.) MSP full record

Spontaneous Generation
http://www.sciencenetlinks.com/lessons.cfm?DocID=126
Digital Library at OSU

This lesson demonstrates that scientific knowledge is stable but also prone to change. Students will understand how those changes can happen in the context of the history of spontaneous generation. This lesson from the American Association for the Advancement of Science aligns with Benchmarks 1 and 10, Nature of Science and History of Science. It can be carried out as a class lesson or as an independent study. Part of the lesson involves students accessing related information on the Internet. Thorough teacher background information and pedagogically sound, structured discussion questions are provided. MSP full record

No. 622: Ignaz Philipp Semmelweis
http://www.uh.edu/engines/epi622.htm
Digital Library at OSU

The University of Houston's College of Engineering presents this series, called Engines of Ingenuity, about creative people and the machines "that make our civilization run." This episode is available in audio format. It recounts the story of Semmelweis's observations regarding contagious disease and the variables he believed could be controlled to prevent spreading of childbed fever. MSP full record

No. 74: Germs
http://www.uh.edu/engines/epi74.htm
Digital Library at OSU

Also from the series Engines of Ingenuity, this page recounts the contributions of various persons to the eventual development of the germ theory of disease. MSP full record

Germy Surfaces
http://www.sciencenetlinks.com/sci_update.cfm?DocID=202
Digital Library at OSU

In this Science Update from Science Netlinks, students will find out how long a germ can hang around and wait for its next victim. MSP full record

Microbes 2: Louis Pasteur -- a Microbe Discoverer
http://www.sciencenetlinks.org/lessons.cfm?BenchmarkID=10%26DocID=236
Digital Library at OSU

This site focuses on Pasteur and his discovery of microorganisms. Middle school students may not be able to imagine a world in which people did not know germs existed, because, in general, students have difficulty understanding that the beliefs, values, attitudes, and points of view of people in the past were different from those today. MSP full record

Who Done It? Or What's That Brown Fuzzy Stuff on My Plum? Koch's Postulates for Proof of Pathogenicity
http://www.apsnet.org/education/K-12PlantPathways/TeachersGuide/Activities/BrownRot/Top.htm
Digital Library at OSU

A safe and simple exercise uses Koch's postulates to prove that an observed fungus is the cause of fruit disease. Since the fungus that causes brown rot of stone fruit (e.g., apricots, peaches, nectarines, plums, and cherries) is present naturally on the surface of these fruit, stone fruit purchased from the supermarket will usually develop the disease. The fungi responsible for brown rot are not human pathogens. This lab requires dissecting and compound microscopes. A simplified exercise, without cultures, to demonstrate the germ theory also is described. MSP full record

Louis Pasteur: Preventing Disease
http://video.google.com/videoplay?docid=5536482817979036751
Digital Library at OSU

This short video clip takes the viewer on site to where Pasteur conducted his famous anthrax experiment. We recommend using the video as a re-enforcement rather than an introduction because it discloses Pasteur's procedure and results, reducing students’ incentive to participate in inquiry regarding what Pasteur might have hypothesized and how he might have tested his hypotheses. MSP full record


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Copyright November 2007 — The Ohio State University. This material is based upon work supported by the National Science Foundation under Grant No. 0424671. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.

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